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Light-sheet microscopy

Light-sheet microscopy

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Micro swimmer

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Muscle oscillations & waves

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Home posts: Science

Minimic side view

<img width="150" height="150" src="https://sguenther.eu/wp-content/uploads/2019/06/minimic-150x150.jpg" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Minimic side view" data-attachment-id="1930" data-permalink="https://sguenther.eu/minimic/minimic-sideview/" data-orig-file="https://sguenther.eu/wp-content/uploads/2019/06/minimic.jpg" data-orig-size="1250,1250" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Minimic" data-image-description="<p>Side view of the <em>minimic</em>. An <a href="https://www.intuity.de/minimic-intelligenter-laborhelfer-fuer-routinemikroskopie/" target="_blank" rel="noopener noreferrer">Intuity</a> project for a better world: <a href="https://www.minimic.com" target="_blank" rel="noopener noreferrer">minimic.com</a>.</p> " data-medium-file="https://sguenther.eu/wp-content/uploads/2019/06/minimic-300x300.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2019/06/minimic-1024x1024.jpg" />

Heidelberg exhibition poster

<img width="102" height="150" src="https://sguenther.eu/wp-content/uploads/2016/09/lifeinperspective_heidelberg_exhibition_poster_2-102x150.jpg" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Heidelberg exhibition poster" data-attachment-id="1731" data-permalink="https://sguenther.eu/data/life-in-perspective/heidelberg_exhibition_poster_2/" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/09/lifeinperspective_heidelberg_exhibition_poster_2.jpg" data-orig-size="1784,2635" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Heidelberg exhibition" data-image-description="<p>We perceive our world as a three-dimensional reality. A truism forms the basis of “Life in Perspective”. The exhibition places the beauty of nature in the center using 3D posters about micro-organisms, thus translating the micro world into a familiar imagery. It is a change in perspective, which visualizes science in a comprehensive way by means of photography and computer design approaching an artistic dimension.</p> " data-medium-file="https://sguenther.eu/wp-content/uploads/2016/09/lifeinperspective_heidelberg_exhibition_poster_2-203x300.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2016/09/lifeinperspective_heidelberg_exhibition_poster_2-693x1024.jpg" />

Life in perspective - cover

<img width="150" height="150" src="https://sguenther.eu/wp-content/uploads/2016/06/lifeinperspective_cover-150x150.jpg" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Life in perspective - cover" data-attachment-id="1086" data-permalink="https://sguenther.eu/data/life-in-perspective/lifeinperspective_cover/" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/06/lifeinperspective_cover.jpg" data-orig-size="2100,2100" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Life in perspective – cover" data-image-description="<p>Zebrafish embryo showing cell membranes in yellow and nuclei in magenta. Image was recorded by Dimitri Kromm at EMBL Heidelberg.</p> " data-medium-file="https://sguenther.eu/wp-content/uploads/2016/06/lifeinperspective_cover-300x300.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2016/06/lifeinperspective_cover-1024x1024.jpg" />

Life in Perspective

Embryonic imaging

<img width="150" height="150" src="https://sguenther.eu/wp-content/uploads/2016/04/mousescope-150x150.jpg" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Embryonic imaging" data-attachment-id="346" data-permalink="https://sguenther.eu/?attachment_id=346" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/04/mousescope.jpg" data-orig-size="2048,2048" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Embryonic imaging" data-image-description="<p>The image shows the cell’s nuclei from four time points of mouse embryonic development. In time the embryo grows and the number of cells increases. In the last time point also the cell membranes are shown.</p> " data-medium-file="https://sguenther.eu/wp-content/uploads/2016/04/mousescope-300x300.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2016/04/mousescope-1024x1024.jpg" />

Embryonic imaging

Widefield vs confocal

<img width="150" height="150" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Widefield vs confocal" data-attachment-id="344" data-permalink="https://sguenther.eu/science/light-sheet-microscopy/confocal-2/" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/04/confocal.jpg" data-orig-size="1900,1900" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Widefield vs confocal" data-image-description="" data-medium-file="https://sguenther.eu/wp-content/uploads/2016/04/confocal-300x300.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2016/04/confocal-1024x1024.jpg" srcset="https://sguenther.eu/wp-content/uploads/2016/04/confocal-150x150.jpg, https://sguenther.eu/wp-content/uploads/2016/04/confocal-150x150@2x.jpg 2x" />

Quality images rock

Lineage specification

<img width="150" height="150" src="https://sguenther.eu/wp-content/uploads/2016/04/venustrap-150x150.jpg" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Lineage specification" data-attachment-id="345" data-permalink="https://sguenther.eu/?attachment_id=345" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/04/venustrap.jpg" data-orig-size="1024,1024" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Lineage specification" data-image-description="<p>Embryonic and extra-embryonic cell lineages in mouse blastocyst. Image was recorded and visualized by Laura Panavaite at EMBL and used as a cover in <a href="http://embor.embopress.org/content/16/8.cover-expansion" target="_blank">EMBO reports 16 (8)</a>.</p> " data-medium-file="https://sguenther.eu/wp-content/uploads/2016/04/venustrap-300x300.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2016/04/venustrap.jpg" />

Lineage specification

<img width="150" height="150" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Dorsal closure" data-attachment-id="347" data-permalink="https://sguenther.eu/?attachment_id=347" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/04/schnurri.jpg" data-orig-size="2510,2510" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Dorsal closure" data-image-description="" data-medium-file="https://sguenther.eu/wp-content/uploads/2016/04/schnurri-300x300.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2016/04/schnurri-1024x1024.jpg" srcset="https://sguenther.eu/wp-content/uploads/2016/04/schnurri-150x150.jpg, https://sguenther.eu/wp-content/uploads/2016/04/schnurri-150x150@2x.jpg 2x" />

Epithelial tissue

Multi-view microscopy

<img width="150" height="150" src="https://sguenther.eu/wp-content/uploads/2016/04/muvispim-150x150.png" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Multi-view microscopy" data-attachment-id="218" data-permalink="https://sguenther.eu/science/light-sheet-microscopy/muvispim/" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/04/muvispim.png" data-orig-size="1725,1722" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Multi-view microscopy" data-image-description="<p>For multi-view imaging optical transparent access to the <em>Drosophila melanogaster</em> embryo is guaranteed through a gel that is nearly transparent in water.</p> " data-medium-file="https://sguenther.eu/wp-content/uploads/2016/04/muvispim-300x300.png" data-large-file="https://sguenther.eu/wp-content/uploads/2016/04/muvispim-1024x1022.png" />

Multi-view microscopy

<img width="150" height="88" src="https://sguenther.eu/wp-content/uploads/2016/06/sarcomere-150x88.jpg" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Sarcomere" data-attachment-id="1079" data-permalink="https://sguenther.eu/science/muscle-waves/sarcomere/" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/06/sarcomere.jpg" data-orig-size="2048,1200" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Sarcomere" data-image-description="<p>Schematics of striated muscle sarcomeres. Bundles of myosin motors are shown in blue, while actin filaments are red. In activated muscles bound myosin motors walk to the plus ends of the actin filaments shortening space between the Z-discs, which represents a sarcomere.</p> " data-medium-file="https://sguenther.eu/wp-content/uploads/2016/06/sarcomere-300x176.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2016/06/sarcomere-1024x600.jpg" />

Sarcomere dynamics

<img width="150" height="150" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Micro-swimmer" data-attachment-id="332" data-permalink="https://sguenther.eu/science/micro-swimmer/swimmer/" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/04/swimmer.jpg" data-orig-size="1755,1284" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Micro-swimmer" data-image-description="" data-medium-file="https://sguenther.eu/wp-content/uploads/2016/04/swimmer-300x219.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2016/04/swimmer-1024x749.jpg" srcset="https://sguenther.eu/wp-content/uploads/2016/04/swimmer-150x150.jpg, https://sguenther.eu/wp-content/uploads/2016/04/swimmer-150x150@2x.jpg 2x" />

Spontaneous waves

<img width="150" height="150" class="attachment-thumbnail size-thumbnail wp-post-image" alt="Spontaneous waves" data-attachment-id="339" data-permalink="https://sguenther.eu/science/muscle-waves/spontwaves/" data-orig-file="https://sguenther.eu/wp-content/uploads/2016/04/spontwaves.jpg" data-orig-size="2100,1953" data-comments-opened="0" data-image-meta="{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}" data-image-title="Spontaneous waves" data-image-description="" data-medium-file="https://sguenther.eu/wp-content/uploads/2016/04/spontwaves-300x279.jpg" data-large-file="https://sguenther.eu/wp-content/uploads/2016/04/spontwaves-1024x952.jpg" srcset="https://sguenther.eu/wp-content/uploads/2016/04/spontwaves-150x150.jpg, https://sguenther.eu/wp-content/uploads/2016/04/spontwaves-150x150@2x.jpg 2x" />